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It is likely that oleacein inhibits ACE in an irreversible manner or acts as a tight binding inhibitor

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Furthermore, metabolic imaging employing fluorescence lifetime imaging (FLI) microscope revealed significant changes in Clpp-deficient oocyte metabolism, including those in the lifetimes of FAD (flavin adenine dinucleotide), NAD (nicotinamide adenine dinucleotide) and the protein-bound percentage of NADH, reflecting disruptions in mitochondrial electron transport chain activity 172